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J Nucl Med. 2008; 49 (Supplement 1):92P
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General Clinical Specialties: Pulmonary

PET, Ventilation-Perfusion

The relationship between lifestyle and SUV value of reactive mediastinal and hilar lymphadenopathy in preventive health screening PET/CT images

Won hyoung Lee1, Joo hyun Oo1, Ie ryung Yoo1, Sung yong Lee1, Sung hoon Kim1 and Soo kyo Chung1

1 Radiology, The Catholic University of Korea, Seoul, South Korea

364

Objectives: To know the relationship between lifestyle (smoking, drinking, living place, and age), and reactive lymphadenopathy in mediastinal and hilar regions interpreted as normal in preventive health check-up PET/CT scans.

Methods: From Oct. 1, 2005 to Sep. 28, 2007, 865 people had PET/CT scan for preventive health check up. Cases with mediastinal and hilar regional lymphadenopathies in the absence of other lung lesions such as pulmonary or mediastinal diseases or their squelae (example: tuberculosis scar, thymoma, pneumonitis) were selected. Total of 37 cases (mean age: 61.2, dev: 9.49, men: 23, women: 14) were included. Peak SUV of mediastinal and hilar lymph nodes were recorded. Person’s lifestyle factors were noted: history of smoking, drinking, location of house (city or county), and age. Relationship with the peak SUV value and lifestyle was examined by multiple regression analysis.

Results: There was no significant relationship between the peak SUV of mediastinal and hilar regions and smoking history (p=0.988), drinking (p=0.886), or living place (p=0.990). Only age had statistically linear relationship with the peak SUV of mediastinal and hilar regions (R square value=0.118, p=0.038, peak SUV=0.968 + 0.023 x age).

Conclusions: Age is the only factor related with the peak SUV of mediastinal and hilar regions on otherwise normal preventive health check-up PET/CT images. Therefore, in the elderly especially, care must be taken to avoid false-positive results for mediastinal and hilar lymphadenopathies in interpreting preventive health check-up PET/CT images.





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Right arrow Articles by Lee, W. h.
Right arrow Articles by Chung, S. k.