| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
|
|
|||||||||
|
|
Technologist Student AbstractsTechnologist Student Papers III |
1 Nuclear Medicine, Evanston Northwestern Healthcare, Evanston, Illinois
2229
Objectives: To determine the effectiveness of saline flushing on 99mTc-Tetrofosmin, 99mTc-Sestamibi, and 99mTc-Medronate syringes for maximum dose administration. To compare the extent of 99mTc-Tetrofosmin residual activity in syringes from two leading vendors.
Methods: Percent residual activities were measured from 99 patient doses. Residual activity was measured for: 99mTc-Tetrofosmin no flush of syringe n=26, one flush of syringe n=25; 99mTc-Sestamibi no flush of syringe n=15, one flush of syringe n=7; 99mTc-Medronate no flush of syringe n=7, one flush of syringe n=19. Average residual percent difference was 15.7% no flush vs. 12.6% one flush for 99mTc-Tetrofosmin (t=4.6, p=0.0), 13.6% no flush vs. 5.8% one flush for 99mTc-Sestamibi (t=3.8, p=0.0) and 6.7% no flush vs. 1.9% one flush for 99mTc-Medronate (t=4.7, p=0.0). Residual activities from 99mTc-Tetrofosmin were measured from two separate suppliers, respectfully named vendor A: n=25 and vendor B: n=25. Syringe residual activity was measured following injection without flushing. Average residual activity was 12.6% vendor A and 8.0% vendor B (t=7.3,p=0.0).
Results: There is significant residual activity in syringes that had no flush with mean residual of 12% for the combined 99mTc labeled isotopes. The range of residual was from 4.6% to 17.3% with a mean of 6.8%. It was also discovered that vendor A had a lower binding percentage of 99mTc-tetrofosmin.
Conclusions: Flushing of syringes with saline statistically results in an increased dose administration. Statistical evidence suggests that users practice syringe flushing to ensure maximum dose administration.
| ||||||||||||||||||||||||||||||||||||||
