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Technologist AbstractsTechnologist Posters |
1 Radiology, Michigan State University, East Lansing, Michigan
2113
Objectives: The purpose is to determine the impact breath-hold respiratory-gated PET/CT imaging has on pulmonary and hepatic lesion characterization and localization.
Methods: 20 patients received whole body PET/CT scans(10-18 mCi FDG iv, 60 min uptake period, GE DSTE). During the whole body PET/CT scan, the patients were instructed to lie still and maintain quiet respiration. The patient was repositioned in the PET scanner detector field, and breath-hold respiratory-gated dynamic images were obtained centered over the identified lesions. Breath-hold respiratory-gated dynamic PET images, (12 frames, 15 sec length) were acquired, alternating the frames between breath-hold and free breathing. The 6 frames of breath-hold data were summed, and this data was attenuation corrected to the separate inspiratory breath-hold CT of the chest and upper abdomen. Images that required adjustments in alignment were done using an Attenuation Correction Quality Control program.
Results: SUVmax:Whole body PET/CT (4.66 +/-2.58),Respiratory-gated PET/CT (4.57 +/-3.56). In patients where the SUVmax decreased from whole body PET/CT to respiratory-gated technique, the mean SUVmax was 3.34 +/- 2.26. In patients where the SUVmax increased from whole body PET/CT to respiratory-gated technique, the mean SUVmax was 7.86 +/- 4.09. The mean shift of respiratory-gated PET/CT was equal or less than whole body PET/CT in 16 of 20 cases.
Conclusions: Using the breath-hold respiratory-gated technique, there was a higher contrast between high uptake lesions and low uptake lesions which may improve lesion characterization even though the mean SUVmax was not significantly different, and an equal or smaller shift in 16 of 20 cases which may improve lesion localization.
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