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J Nucl Med. 2008; 49 (Supplement 1):408P
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Instrumentation & Data Analysis: Instrumentation

Instrumentation Posters

HiSens: A new architecture for pixelated solid state gamma camera

Lucie Guérin1, Loïck Verger1 and Véronique Rebuffel1

1 CEA/LETI/DTBS/SDT/LDET, Grenoble, France

1716

Objectives: Collimator and detector are the main limitations of the system performance of the NaI based standard Anger gamma camera. The future generation of gamma cameras will combine new collimator and new solid state detector with the objective to overcome the sensitivity-spatial resolution trade off. The proposed HiSens (High Sensitivity) architecture is an original architecture combining a new geometry of the static large parallel hole collimator associated with a pixellated CdZnTe detector providing depth of interaction (DOI) information and an adapted method of reconstruction.

Methods: HiSens performances have been evaluated by simulation after the development of SINDBAD software and an adapted method of iterative reconstruction (based on OSEM algorithm) using the DOI information at different virtual layers of the detector. HiSens architecture has been studied with a 3D thyroid phantom at 10 cm from the collimator in planar acquisition mode and with a 3D phantom in tomographic acquisition mode.

Results: We have considered a 5 mm-thick CdZnTe detector composed either of five equal-thickness layers or of three equally-probable-thickness layers, and a configuration of 4 pixels per collimator hole (0.75 mm pitch). We have simulated a "HiSens" collimator with a hole height reduction allowing to have a gain of 5 in term of system sensitivity in comparison to the standard Anger gamma camera. For the considered phantoms, in both planar or tomographic acquisition mode, the HiSens architecture allows to recover the system spatial resolution for a gain of 5 of the system sensitivity.

Conclusions: Thanks to HiSens architecture, the system sensitivity and system spatial resolution tradeoff is improved due to the configuration of several pixels per collimator hole, and to the integration of DOI information into the planar and tomographic image reconstruction method for 3D phantoms.





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Right arrow Articles by Rebuffel, V.