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J Nucl Med. 2008; 49 (Supplement 1):407P
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Instrumentation & Data Analysis: Instrumentation

Instrumentation Posters

Simulated imaging studies of C-SPECT/CT

Caesar Ordonez1, Jinhua Sheng1, Yusheng Li1 and Wei Chang1

1 Diagnostic Radiology, Rush University Medical Center, Chicago, Illinois

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Objectives: Use simulations to guide the design and characterize imaging performance of a proposed cardiac SPECT/CT system.

Methods: The C-SPECT/CT (formerly called MarC-SPECT) is based on a large stationary C-shaped detector and collimator assembly that surrounds a patient sitting upright on a smart-chair. The system acquires simultaneously a large number of projections for a predetermined image volume (PIV) that encloses the heart. Simulated emission (ECT) and transmission (CT) data were generated from appropriately-built digital phantoms, subject to variations in system design parameters (such as geometry and sampling scheme). These projection data were then reconstructed with the OS-EM algorithm, with corrections for the effects of attenuation and distance-dependent resolution. Attention was focused on determining the optimal angular coverage, and investigating the effects of uneven angular and linear sampling in the projections, and small sampling gaps in the detector system. We also studied the effects of truncated projections: for ECT, in the presence of hot source outside the reconstruction PIV; and for TCT, when the thorax is larger than the PIV. The effects of noise and scatter were not included in our studies.

Results: The optimal angular coverage for C-SPECT/CT is about 210° with respect to the center of the PIV, as a practical compromise between hardware design and image quality. Images reconstructed with OS-EM from truncated projections showed no significant artifacts inside the PIV. Preliminary investigations of reconstruction from hybrid data that complement truncated projections within the PIV with non-truncated, high-sensitivity/low-resolution projections appear promising to correct for the remaining errors.

Conclusions: C-SPECT/CT promises high-quality SPECT imaging.

Research Support: NIH





This Article
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Right arrow Email this article to a friend
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Right arrow Alert me to new issues of the journal
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Right arrow Articles by Ordonez, C.
Right arrow Articles by Chang, W.
PubMed
Right arrow Articles by Ordonez, C.
Right arrow Articles by Chang, W.