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J Nucl Med. 2008; 49 (Supplement 1):404P
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Instrumentation & Data Analysis: Instrumentation

Instrumentation Posters

Performance evaluation of the Siemens Inveon microPET system

Nadege Dartial1, Thomas Carlier2, Dimitris Visvikis5, Sébastien Jan4, Marion Fuselier3, Jean-Claude Desfontis3, Jacques Barbet1 and Manuel Bardies1

1 INSERM Unit 601, Nantes, France; 2 Nuclear Medicine, University Hospital of Nantes, Nantes, France; 3 National Veterinary School, Nantes, France; 4 Frédéric Joliot Hospital, Orsay, France; 5 INSERM Unit 650, Brest, France

1703

Objectives: The aim of this study was to evaluate the performance of the Siemens Inveon microPET.

Methods: Spatial resolution (SR) was measured with a 18F line source (0.5 mm inner diameter). Absolute sensitivity was obtained with a 22Na point source using two energy windows (250-750 keV, 350-650 keV) together with two timing windows (2.8 ns and 4.7 ns). SR and sensitivity were moved axially from 0 to 6 cm and radially from 0 to 4 cm. An evaluation of the count rates was performed using a "rat" and a "mouse" sized phantom filled uniformly with 18F. Noise equivalent count rates (NECR) were subsequently calculated. Image quality was assessed with an 1-hour acquisition of a "hot-rod" mini-Derenzo phantom filled with 8 MBq of 18F.

Results: SR ranged radially from 1.9 mm (respectively 2.0 mm for the tangential evaluation) at the centre of the FOV (cFOV) to 2.2 mm (resp. 3.1 mm) at 40 mm offset. In the axial direction SR reached 2.0 mm (resp. 1.8 mm) at an axial offset of 50 mm from the cFOV. Absolute sensitivities at the cFOV are reported in the table below. Considering the image quality study, the 1.6 mm diameter hot-rod was visible but the 1.2 mm hot-rod was not resolved.

Conclusions: The performance of the Siemens Inveon microPET was evaluated showing excellent sensitivity and SR. Additional measurements are planned to determine the NECR curve for mouse and rat phantoms with a variable length sizes to more extensively evaluate out of the FOV contributions (rat phantom).


Figure 1





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