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Assessment of heart motion during respiration with cine CT without gating in cardiac PET

¹ U.T.M.D. Anderson, Houston, Texas; ² U.T. Medical School, Houston, Texas

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Objectives: Average CT (ACT) from cine CT without respiratory gating can improve the registration between PET and CT data sets on PET/CT. From the same cine CT, we designed a new max-min intensity projection (MmIP) CT image to assess the heart motion of 33 non small cell lung cancer (NSCLC) patients, and compared with the heart motion of 33 other patients from breath hold (BH) cardiac CT.

Methods: 33 NSCLC patients were scanned with cine CT on a GE PET/CT scanner. The cine scan duration was one breath cycle plus 1 s. The gantry rotation was 0.5 s. We first obtained the maximum and minimum intensity projection CT images (MIP and mip) from the cine CT images at the same slice location, and averaged the MIP and mip CT images for a single MmIP CT image, which can be used to demarcate the heart positions at the end-inspiration and end-expiration phases. The measurement was performed on the coronal slice of the MmIP CT image centered at the aortic valve. The motion extents in the superior and lateral direction were measured. We also measured another 33 patients who underwent ECG gated 64-slice cardiac CT at gantry rotation of 0.35 s with breath hold and iodine contrast injection.

Results: The new MmIP CT was effective in showing the heart positions at end-inspiration and end-expiration phases. The average superior and lateral motions of the heart during respiration were 1.1 and 1.0 cm, respectively, and at breath hold were 0.7 and 0.3 cm, respectively. The standard deviations for the superior and lateral motions during respiration were both 0.5 cm, and at breath hold were 0.2 cm.

Conclusions: New MmIP image from cine CT can be used to assess heart motion. Compared with the baseline breath-hold data, respiratory motion induced additional superior and lateral heart motion of 0.4 and 0.7 cm, respectively.

This Article Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Pan, T. Articles by Macapinlac, H. PubMed Articles by Pan, T. Articles by Macapinlac, H.