SNM Annual Meeting Abstracts
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     



J Nucl Med. 2008; 49 (Supplement 1):372P
This Article
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Google Scholar
Right arrow Articles by Jeong, S. Y.
Right arrow Articles by Bom, H.-S.
PubMed
Right arrow Articles by Jeong, S. Y.
Right arrow Articles by Bom, H.-S.

Oncology-Clinical Diagnosis: Solid Tumors

Clinical Diagnosis-Solid Tumors Posters

F-18 FDG PET/CT using diuretics and bladder catherization for detection of bladder cancer local recurrence

Shin Young Jeong1, Ari Chong1, Jung-Min Ha1, Young-Soon Seo1, Seong-Young Kwon1, Jung-Joon Min1, Ho-Chun Song1 and Hee-Seung Bom1

1 Nuclear Medicine, Chonnam National University Hospital, Gwang-ju, South Korea

1570

Objectives: The purpose of this study was to investigate the role of PET/CT in the detection of locally recurrent bladder cancer using diuretics and bladder catherization to remove the excreted F-18 FDG from the bladder.

Methods: Thirteen patients with bladder cancer (mean age : 68±10 y, 10 males) underwent PET/CT for recurrence detection. All patients had been previously submitted to primary tumor resection by transurethral resection. Histopathology confirmed transitional cell carcinoma in all cases. Diuretics (20mg of furosemide) was injected intravenously 20 min after F-18 FDG injection. Bladder catherization were performed before image acquisition. PET/CT findings were confirmed by MRI, cystoscopy, or biopsy.

Results: In PET/CT using diuretics and bladder catherization, normal bladder wall activity was similar to pelvic muscle. Hypermetabolic lesions could be easily detected by PET and precisely localized in the bladder wall. PET/CT was able to detect hypermetabolic bladder lesions in 7 of 13 patients. Recurrences were confirmed by cystoscopic biopsy (4 of 7), radical cystectomy (1 of 7) and MRI study (2 of 7). In 6 of 13 patients, bladder wall activity was similar to pelvic muscle. Cystoscopy and MRI were performed in 6 patients. Small papillary mass was found in 1 of 6 patient and was confirmed locally recurrent bladder cancer. PET/CT using diuretics and bladder catherization was showed sensitivity 87.5%, specificity 100%, accuracy 92.3% and false negative rate 12.5%.

Conclusions: PET/CT images after diuretics and bladder catherization were able to overcome the difficulties posed by the urinary excretion of F-18 FDG. PET/CT with diuretics and bladder catherization can be used for detection of locally recurrent bladder cancer.





This Article
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Google Scholar
Right arrow Articles by Jeong, S. Y.
Right arrow Articles by Bom, H.-S.
PubMed
Right arrow Articles by Jeong, S. Y.
Right arrow Articles by Bom, H.-S.