| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
|
|
|||||||||
|
|
Oncology-Clinical Diagnosis: Solid TumorsClinical Diagnosis-Solid Tumors Posters |
1 Nuclear Medicine, University Hospital, Udine, Italy
1529
Objectives: To determinate whether DTP can predict LCST.
Methods: 208 pulmonary cancer pts were studied: 87 had squamous cell cancer (SCC), 69 adenocarcinoma (AC), 17 indifferentiate cancer (IC), 8 small cell lung cancer (SCLC), 18 bronchioloalveolar cancer (BC) and 9 neuroendocrine cancer (NC). Early (1 h)(E), delayed (2 h) (D) SUV and Retention Index (RI) were calculated.
Results: E-SUVs, D-SUVs and RI were in SCC: 11.9±5.1; 15.1±6.3 and 30.0%±22.5%; in AC: 8.9±4.5; 11.2±5.7 and 28.4%±17.5%; in IC: 17.8±7.8; 20.0±10.3 and 27.7%± 11.2%; in SCLC: 11.1±4.8; 14.3±4.9 and 34.8%± 22.2%; in BC: 5.4±2.5; 6.8±3.6 and 22.5%± 29.0%; in NC: 4.7±3.0; 5.4±3.4 and 12.9%± 22.3% respectively. SUV over time increased in all pts with IC and SCLC and decreased in 22% of pts with NC, in 17% with BC, in 4% with AC and in 2% with SCC and the decrease was higher in pts with BC (-22,9%) and NC (-21%) than in pts with SCC (-10,1%) and AC (-3,3%).
Conclusions: Higher E-SUV are suggestive of IC; lower E-SUV are more frequent in BC and NC, while intermediate E-SUV are found in SCC, AC and SCLC, which toghether with IC have the highest RI. A SUV decrease over time, exspecially when more pronunced, is suggestive of BC or NC. These findings support a difference in the dynamics of FDG uptake over time in different LCST. RI might have a role in identifying the degree of tumour aggressiveness.
| ||||||||||||||||||||||||||||||||||||||
