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J Nucl Med. 2008; 49 (Supplement 1):352P
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Oncology-Clinical Diagnosis: Solid Tumors

Clinical Diagnosis-Solid Tumors Posters

Validity of F-18 FDG-PET/CT and contrast-enhanced MDCT in detecting recurred gastric cancer: Analysis according to individual lesions

Jung-Min Ha1, Shin Young Jeong1, Young-Soon Seo1, Seong-Young Kwon1, Ari Chong1, Jung-Joon Min1, Yong-Yeon Jeong2, Ho-Chun Song1 and Hee-Seung Bom1

1 Nuclear Medicine; 2 Radiology, Chonnam National University Hospital, Gwang-ju, South Korea

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Objectives: We assessed diagnostic accuracy of F-18 FDG-PET/CT (PET/CT) and contrast-enhanced MDCT (CECT) in detecting tumor recurrence of gastric cancer.

Methods: One hundred-ten patients (72 M, 38 F, mean age; 59.2 y), who had undergone surgery for gastric cancer, were included. Forty eight patients were confirmed to have recurred gastric cancer by pathology or clinical follow-up. All PET/CT and CECT images were analyzed according to individual lesions in anastomotic site, regional LN, distant metastasis and peritoneal seeding. Distant metastatic lesions included those in liver and in other solid organs (ovary, colon, adrenal gland. etc), paraaortic and/or retroperitoneal LNs.

Results: Total of 62 lesions were found to have tumor recurrence; anastomic sites (n=15), reginal LNs (n=5), retroperitoneal and/or paraaortic LNs (n=16), liver (n=9), other solid organs (n=5), and peritoneal seeding (n=10). In anastomic site, the sensitivity, specificity and accuracy of PET/CT and CECT were 73%, 98%, 95% and 53%, 100%, 94%, respectively. in regional LN, 80%, 100%, 99% and 80%, 98% 97%, respectively. In liver, all 100% in PET/CT and 88.9%, 96%, 95% in CECT, respectively. In other solid organ, 40%, 97%, 95% and 80%, 97%, 96%, respectively. In peritoneal seeding, 60%, 99%, 95% in PET/CT and all 100% in CECT, respectively.

Conclusions: PET/CT showed better diagnostic accuracy in detecting recurred gastric cancer than CECT which was more sensitive and specific in detecting other solid organ metastasis and peritoneal seeding. Therefore, when patients are suspected to have recurred or metastatic gastric cancer, additional CECT may be required to diagnose peritoneal seeding and solid organ metastasis.





This Article
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Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
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Google Scholar
Right arrow Articles by Ha, J.-M.
Right arrow Articles by Bom, H.-S.
PubMed
Right arrow Articles by Ha, J.-M.
Right arrow Articles by Bom, H.-S.