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J Nucl Med. 2008; 49 (Supplement 1):324P
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Oncology-Basic Science: Therapy, Metrics & Intervention

Therapy, Metrics & Intervention Posters

Standard uptake value (SUV) of normal organs in 250 patients on FDG-PET imaging

Sabri Zincirkeser1, Metin Halac2, Ertan Sahin1, Guliz Durak1, Umut Elboga1, Zehra Kurt1 and Nese Dogan1

1 Nuclear Medicine, Gaziantep University Medicine School, Gaziantep, Turkey; 2 Nuclear Medicine, Istanbul Univ. Cerahpasa Medicine School, Istanbul, Turkey

1372

Objectives: Standardised uptake values (SUVs) of normal organs in 250 patients were evaluated by 18F-FDG (fluoro-deoxyglucose)-PET/CT (Positron Emission Tomography and Computed Tomography).

Methods: Two hundred fifty patients without any non-physiological 18F-FDG uptake were joined into the study. There were 143 males and 107 females. In male; patient ages ranged from 22 years to 83 years (mean age, 58 years ±16 ), body weights ranged from 47 to117 kg (mean,71 kg±11) and mean plasma glucose values at the time of the study were 114mg/dl ±16. In female; patient ages ranged from 17 years to 79 years (mean age, 50 years ±14 ), body weights ranged from 45 to111 kg (mean,65 kg±13) and mean plasma glucose values at the time of the study were 108mg/dl ±21. All patients fasted for at least 4 hours before imaging and their fasting blood sugar level was within the normal range. Whole-body PET-CT imaging was performed with the PET-CT system and acquisition was performed after intravenous administration of 18F-FDG and images obtained from the vertex to the upper thigh region. The SUVs of various organs were determined from the transvers views.

Results: The highest 18F-FDG uptakes were found in the cerebrum, cerebellum, myocardium, tonsils,liver, spleen in both sex. Conclusion: Having knowledge of physiological 18F-FDG uptake and SUVs are needed for interpretation of whole-body 18F-FDG –PET studies.

Conclusions: Having knowledge of physiological 18F-FDG uptake and SUVs are needed for interpretation of whole-body 18F-FDG –PET studies.





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