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General Clinical Specialties: PediatricsPediatrics Posters |
1 Children's Hospital, Harvard Medical School, Boston, Massachusetts
1174
Objectives: To evaluate if controlling room temperature prior to and during absorption of tracer as well as during imaging would affect tracer uptake in brown fat in children.
Methods: We reviewed all FDG-PET scans done after the ambient temperature in the injection room and imaging room was increased to 75° F. All studies were performed for evaluation of cancer. Total of 10 patients (7-24 years) had FDG-PET scan during this period. None of these patients received pre-medications. The minimum outside temperature on the days that these studies were performed ranged from 7° F to 29° F with an average minimum temperature of 23° F. Sixty minutes after intravenous administration of 150 uCi/kg (5.55 MBq/Kg) of 18F FDG, attenuation corrected PET images of the torso were acquired in 2D mode on a GE Advance Nxi PET scanner (GE Healthcare Technologies, Waukesha, WI). This data was compared to 25 randomly selected patients who had FDG-PET scans prior to initiation of injection and imaging room temperature control on days with similar minimum average temperature (24° F).
Results: None of the patients that had a FDG-PET scan performed after initiation of room warming had demonstrable brown fat uptake. In comparison, 13 of the 25 patients done prior to warming the room had mild to moderate brown fat uptake. This is difference is statistically significant (p<0.003).
Conclusions: The value of controlling the room temperature at 75° F is clearly demonstrated in this small group of pediatric patients and should be seriously considered when imaging the pediatric population.
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