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J Nucl Med. 2008; 49 (Supplement 1):271P
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General Clinical Specialties: Musculoskeletal

Musculoskeletal Posters

Prospective evaluation of the diagnostic value of SPECT/CT

Rosalie Babicheva1, Quee Li Chiam1, Kien Lee1, Hugh Dixson1, Chuong Bui1, Andrew Nguyen1, Barry Elison1, Mark Dobson1 and Barbara Bedford1

1 Nuclear Medicine & U/S, Bankstown/Lidcombe Hospital, Bankstown, New South Wales, Australia

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Objectives: Our aim was to evaluate the incremental diagnostic value of a state of the art SPECT/CT camera.

Methods: A six-slice Philips Precedence camera was recently installed so that SPECT studies could have CT for attenuation correction and anatomic localisation. All patients who had SPECT/CT were prospectively entered into the study. Reporting doctors compared the values of SPECT vs SPECT/CT in terms of change in diagnosis, more accurate diagnosis and increase in diagnostic confidence for each patient. CT was performed as part of a combined SPECT/CT scan. CT effective dose (E) of each patient was calculated by using formula E=EDLPxDLP, where DLP=dose-length product and EDLP=region-specific normalised effective dose. Patient BMI was calculated.

Results: There were 160 scans studied: 83 bone scans with 36 change in diagnosis, 56 with more accurate diagnosis and 58 with increased diagnostic confidence, 77 MIBI scans with 6 change in diagnosis, 9 more accurate diagnosis and 32 increase in diagnostic confidence. Patients received an effective dose from the CT component of bone scan ranging from 0.61 mSv to 22.39mSv (mean =5.80mSv, SD=5.04mSv) and of the Tc-99 Sestamibi scan ranging from 0.81mSv to 2.74mSv (mean=1.76mSv, SD=0.38mSv). Patient BMI ranged from 16 to 52 (mean=29). The improvements in change in diagnosis, more accurate results and increase in diagnostic confidence were not adversely affected in this selected group of patients by high BMI nor by low E.

Conclusions: SPECT/CT is clinically helpful with the addition of relatively small extra effective doses from the CT.





This Article
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Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
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Right arrow Articles by Babicheva, R.
Right arrow Articles by Bedford, B.
PubMed
Right arrow Articles by Babicheva, R.
Right arrow Articles by Bedford, B.