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J Nucl Med. 2008; 49 (Supplement 1):269P
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General Clinical Specialties: Musculoskeletal

Musculoskeletal Posters

Quality control of radiosynovectomy (RSO) by SPECT/CT

Michael Wissmeyer1, Harald Bonel2, Bernd Klaeser1, Petar Spanjol1, Dieter Luescher1, Osman Ratib3 and Thomas Krause1

1 Nuclear Medicine; 2 Radiology, University of Berne, Berne, BE, Switzerland; 3 Nuclear Medicine, University of Geneva, Geneva, GE, Switzerland

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Objectives: To evaluate SPECT/CT for quality control of RSO.

Methods: 14 patients (7m, 7f, mean age 52y) underwent a total of 15 RSO of the knee. A mean activity of 186 MBq/joint mixed with 37 MBq Tc-99m-pertechnetate was injected. Subsequently, planar anterior/lateral views and SPECT/CT of the joints were obtained. Two physicians independently read planar and SPECT/CT images using visual scores for overall, compartmental and extraarticular radiopharmaceutical distribution. Percentage of identical findings for overall/compartmental findings and the correlation coefficient (CC) for overall findings were calculated.

Results: SPECT/CT was feasible and could rule out extraarticular soft tissue contamination in all cases. Overall, we found a limited but satisfactory concordance between planar and SPECT/CT imaging (27%, CC=0.689). The best concordance was found for the craniolateral/craniomedial cavities (67%/40%, respectively). Limited accordance was shown for the medial/lateral epicondylar region and for the intercondylar cavity (20%/20%/27%, respectively), probably due to partial overlap with other compartments on planar images. No or only little concordance was observed for the dorsomedial/dorsolateral and for the suprapatellar cavities (0%/7%/7%, respectively), most probably due to poor anatomical discrimination of planar imaging. For the popliteal region, especially for detection of radioactivity in baker cysts, we obtained satisfactory concordances (33%/67%, respectively).

Conclusions: SPECT/CT is a reliable method for quality control of RSO. Due to volumetric data it is superior to planar imaging and may be used for dosimetric issues in the future.





This Article
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Right arrow Email this article to a friend
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Right arrow Alert me to new issues of the journal
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Google Scholar
Right arrow Articles by Wissmeyer, M.
Right arrow Articles by Krause, T.
PubMed
Right arrow Articles by Wissmeyer, M.
Right arrow Articles by Krause, T.