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J Nucl Med. 2008; 49 (Supplement 1):252P
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General Clinical Specialties: General Practice-Oncology

General Practice-Oncology Posters

Applications of SPECT-CT in lymphoscintigraphy

Mehdi Djekidel1, Yassine Kanaan1, Steven Pitt1, Robert Ackerman1, Kirk Frey1 and Richard Brown1

1 Nuclear Medicine/Radiology, U. of Michigan, Ann Arbor, Michigan

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Objectives: The purpose of this exhibit is to demonstrate the utility of SPECT/CT in various applications of lymphoscintigraphy. Issues of timing, technique and corregistration of anatomic and scintigraphic imaging and potential artifacts are discussed.

Methods: Following the intradermal administration of either filtered or unfiltered 99mTc-sulfur colloid both planar and SPECT/CT imaging was performed. The SPECT data was fused with the CT images and viewed in a fused format.

Results: Utilization of SPECT/CT fusion enabled more accurate localization of lymphatic drainage in the pre-operative evaluation of breast, melanoma and chylous leakage. We also encountered a case of a thigh lymphangioma that was more accurately characterized with co-registered SPECT/CT.

Conclusions: Although planar lymphoscintigrapy is useful in defining the path of lymphatic drainage it lacks the added dimension of specific anatomic localization. Fusion imaging with SPECT/CT enables the interpreter to accurately identify whether the drainage is superficial or in the deep soft tissue planes. In cases of suspected chylous leakage it can also determine the location of the leak relative to the IVC and other critical structures.





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