| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
|
|
|||||||||
|
|
General Clinical Specialties: GastroenterologyGastroenterology Posters |
1 Nuclear Medicine; 2 Internal Medicine, MMC, Bronx, New York
|
|
1052
Objectives: Gastric emptying study is the non-invasive physiological study of the gastric emptying and motility functions. Half-time and 4hr retention are used in the diagnosis and treatment of gastric dysmotility. This study aims to compare the half time and 4hr retention with other quantitative parameters.
Methods: Patients with functional dyspepsia who underwent physiologic calorie meal gastric emptying study between Dec 2006 to Dec 2007 (n= 162) were analyzed retrospectively. 1hr, 2hr, 3hr, 4hr retentions and gastric emptying half time were compared for concordance of the results. Early slope (with multiple points from 30 minutes to 2 hrs), late slope (2hr, 3hr and 4hrs endpoints) and over-all slope (all points from 30 min to 4hr intervals) were analyzed.
Results: The Overall concordance of the result across all the end points (1hr, 2hr, 3hr, 4hr and half time) was 98/162 (61%). The similarity matrix showed correlation (r=0.87) between half time and 4hr retention; between 4hr and 3hr retention (r=0.9). ROC analysis showed that early slope to be better predictor with both half time (area 0.91, p=0.01) and 4hr retention (area 0.87, p=0.01).
Conclusions: The various end point retentions and half time were discordant in 39% of the cases. The correlations were not concordant at all levels of emptying with resulting FP and FN cases. The early slope representing the rate of gastric emptying in the first 2 hrs of the study might be a sensitive indicator of abnormal gastric emptying. Further clinical correlation will clarify the role of various patterns of discordant gastric emptying and available treatment options.
| ||||||||||||||||||||||||||||||||||||||
