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Impact of combined scintigraphy and USG interpretation in parathyroid pathologies

¹ Nuclear Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey

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Objectives: The aim of this study was to explore the clinical impact of combined scintigraphy and USG interpretation by nuclear medicine physician in patients with suspected parathyroid pathologies.

Methods: 48 patients referred to nuclear medicine department for suspected parathyroid pathology were prospectively evaluated with parathyroid scintigraphy together with USG. A standard dual-phase parathyroid scintigraphy with SPECT acquisition was performed using Tc-99m MIBI followed by neck USG by nuclear medicine physician. The results of scintigraphy were interpreted and classified as: negative, suspicious and positive. Scintigraphic results were then compared with USG findings and combined interpretation was noted. USG was considered to have a clinical impact on the result of scintigraphy if a low intensity radioactivity retention suspicious for parathyroid adenoma/hyperplasia observed in the scintigraphy was cleared out as a thyroid nodule or as a parathyroid pathology by USG. If the localization of a parathyroid lesion was determined as intratiroidal by USG, it was also accepted as the presence of clinical impact. Finally, the results of combined interpretation were compared with the results of USG evaluation solely performed by a radiologist.

Results: 8 patients had suspicious, 29 negative and 11 had positive scans. Clinical impact of combined interpretation was seen in 9 (20.4%) of 48 patients. Twenty-six patients had USG evaluation performed by a radiologist before and additive effect of combined interpretation was observed in 12 (46.1%) of them especially in the differential diagnosis between lymph node and parathyroid pathology.

Conclusions: Combined interpretation of parathyroid pathologies using both scintigraphy and USG is superior to single scanning or USG.

This Article Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Kara Gedik, G. Articles by Ugur, O. PubMed Articles by Kara Gedik, G. Articles by Ugur, O.