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J Nucl Med. 2008; 49 (Supplement 1):201P
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Cardiovascular: Clinical Science

Clinical Science Posters

Impact of iterative reconstruction (IR), CT attenuation correction (AC) and scatter correction (SC) on myocardial SPECT perfusion images in obese patients

Richard Brunken1, Manual Cerqueira1, Frank DiFilippo1, Richard Full1, Sagar Patel1 and Dalia Ibrahim1

1 Nuclear Medicine, Cleveland Clinic Foundation, Cleveland, Ohio

870

Objectives: Obese patients pose challenges for SPECT perfusion imaging. CT based AC, along with SC, may improve image quality in obese patients. Study goal was to assess the impact of AC with/without SC on SPECT perfusion images in obese subjects.

Methods: SPECT/CT perfusion images were acquired at rest (n-20) and after stress (n=22) on a Siemens Symbia T6 camera in 25 pts (10 men; age 55.6±8.4 yrs, body mass index 46.9 ± 9.3 kg/m2) without significant CAD on invasive (n=23) or CT (n=2) angiography. Image sets were recontructed using standard filtered back-projection (FBP), iterative reconstruction (IR), interative reconstruction with AC (IR-AC) and iterative reconstruction with AC and SC (IR-AC-SC). Two skilled observers blinded to the reconstruction technique each assessed image quality (excellent, good, fair, poor, unreadable) and obtained myocardial counts in 17 std myocardial segments using 4-D MSPECT. Segmental counts were averaged and used to calculate the coefficient of variation.

Results:


Figure 1

Conclusions: In obese subjects, CT based AC improves image uniformity and perceived image quality.





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