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Cardiovascular: Clinical ScienceClinical Science Posters |
1 Nuclear Medicine, Medical University of South Carolina, Charleston, South Carolina
861
Objectives: AC using a gadolinium source has been shown to improve image quality and reduce artifacts. Literature is sparse regarding its significance using VAS. The objective of this study is to compare AC and NAC MPS using VAS of segmental myocardial radiotracer uptake.
Methods: Myocardial perfusion scans of 87 consecutive patients who received gated, dual digital detector, AC single photon emission tomography within 3 months of coronary angiography (CA) were retrospectively analyzed. Both AC and NAC data were re-interpreted by two experienced nuclear physicians, blinded to the results of CA to produce summed difference score (SDS) using a 20-segement VAS [0=normal, 1=slightly reduced, 2=moderately reduced, 3=severely reduced, 4=absent]. Inter-observer difference was resolved with consensus.
Results: 31 of 87 patients had normal CA (< 50% lesion) and were studied with and without AC. Using SDS > 2, AC VAS changed final interpretation in 25.8% (8) of the patients. 7/8 patients were interpreted as normal by AC VAS, but were interpreted abnormal by NAC VAS. One patient was interpreted as having a mild reversible defect with AC VAS, as compared to severe reversible defect by NAC VAS. AC VAS did not produce any perfusion defects that were not seen in NAC VAS.
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Conclusions: Attenuation correction helps resolve artifacts and reduces false positive scans in patients with no known coronary artery disease, thereby helping to minimize1 unnecessary cardiac catheterizations.
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